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Grade distribution for every class as well as average time required for study from prior years is available to students so you can see what you are getting into.
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Grade distribution can be highly misleading though. It doesn't account for people who dropped the class because they were failing (how much of an impact this makes varies by class - some classes have no drops, some have large numbers).
Sophomore exploratory is a wonderful thing, and I encourage anyone going to MIT to take advantage of it.
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Rather than meeting the premed chem requirements with as second semester of organic chem, most med schools will allow you to take biochemistry instead.
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I thought both were required?
Also, 7.05 (that's the bio department's biochem) is absolutely not a gimme. I'm awful at chem, so I'm sure that if I'd taken 5.13 I would have found it much harder than 7.05, but one should not take 7.05 expecting it to be easy.
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Most of your grades come from tests, although some classes have a minor problem set component, so it really matters how good you are at the types of tests the biology and BCS departments administer.
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Yep.
I struggled a lot with the tests (in BCS, primarily). It was very, very frustrating. There were classes where profs would compliment me on my understanding of the material, and then I'd end up with a B or C in the class, based on the tests, while people who had seemed to me to not understand what was going on in class very well got better grades. I will note that my experience in this regard was not typical, and that I still don't understand why I had so much trouble doing well, or even adequately, on the tests.