What's your D's track record, OP, on making good choices? If she's the kind of kid who makes impulsive and/or poorly thought out choices and then regrets them, you may be right to be concerned. ("Getting out of the south" is not, by itself, a great reason to choose a school - I assume there are other reasons?) And you might want to invest some time of your own researching the three schools to make sure she knows all the pros and cons before she commits. If she has a track record that shows self-awareness and good judgement, then she's earned your trust - and even the right to make a mistake if NE doesn't turn out as she hopes.
Picking a college is a relatively low risk decision in the scheme of things. If she hates it, she can transfer. So make sure she understands that there will be no recriminations if it doesn't work out - she should be able to talk to you about her doubts and concerns once she arrives at NE without fear that it will trigger an 'i told you so' reflex, hard though it may be to resist.