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In my very subjective opinion, the prestige/difficulty of your school will afford you 0.2 on your GPA at the very most but usually adcoms don't care. I think school difficulty is overblown anyway since everyone seems to think they go to a tough school. In the event you have exact the same MCAT score, essays, recs, interview, EC's, PS as someone else, then your school might be a tip factor. From my experience, >50% of the people interviewing at top med schools come from a US News Top 20 undergrad so a prestigious college is the norm, not the exception.
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