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Well, from an academic point of view, clearly Case stands above Santa Cruz. Case has a smaller enrollment, they send 9% of their students to med school, and Case has their own med school as well. UCSC is not seen as a top UC so that might ding you a little bit when applying to med school. But UCSC is a 6-hour drive from where you live, the tuition is less (you didn't say what kind of grants and scholarships you have), and so it's more practical than going all the way to Ohio. I think only you can decide if being closer to home and maybe less tuition is important enough to outweigh the academic superiority of Case.
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