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Amherst is definitely the most difficult to get into both ED and RD of the three. JHU is more self-selecting than Colgate, so it may slightly have more accomplished students (more on the SAT side than on the grade side), but also has a higher acceptance rate than Colgate.
I don't know if there's really such a thing as which is best for neuoroscience. Doing well at any three schools will afford you the same opportunities going forward. Go to the schools and talk to the professors and see what feels best to you. This isn't really the type of question that others can answer for you.
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