at first I opened this thread and thought you were a freshman, and I would have say no way!
I think this could be good for a sophomore, though. orgo lab takes up a pretty substantial amount of time, as you probably know.
I think you should be ready to drop microbio lab if you have to, but at least give it a shot. I know some people who took it and it seemed like they were doing really cool stuff, so don't go down without a fight, you know?
last thing: as a sophomore, have you considered trying to get involved with research on campus? do you have an overall career goal? if the answer is no that's totally fine, but if you want to go into research or medicine then you might want to start thinking about contacting labs this year.
(maybe you already are all set with this stuff, and you just want to talk scheduling, in which case that is awesome. if not, consider that if you work in a lab, your scheduling needs/preferences will change depending on the demands there.)