Those Fs in your freshman yr will not look good no matter where you apply, however if the reason was something like illness, family crises, etc make sure it is shown in your applications. A simple short note from your guidance counselor will do the trick. Colleges know that "things can happen" to even the best students.
Colleges also know that the 14 year old is not the person who is coming to their school, the 18 year old is. If it wasn't because of illness, crisis, etc, but rather because you took a while to grow up, continue to make yourself shine by keeping the grades the highest you can, and engage in activities that showcase your maturity, responsibility, etc. Choosing someone who knew you "before" and "after" to write a letter that remarks on how you matured, how reliable you are and so on would be helpful.
Loyola says they regard "character" as very important in making their decisions. Show them you are now what they are looking for.