D's intro Bio was Honors class, which means that it was much smaller and it was taught by 3 profs simultaneusly at every lecture teaching their specialty. She said that there is no way she would have done well in upper division Bio classes, she took many of them including several neuro. She said that all of them were based on this first class. D. had both Honors and AP Bio (5 on exam) at her private prep HS and her Honors HS Bio was using the same textbook as her first college Bio. None of HS Bio was much help in this class, that went thru AP material in a first 2 weeks. So, it is important to talk to pre-med advisor, although at D's school, this class was very well known and many talked about it in D's Honors dorm even before classes began.