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Here's may experience as pre-med: if by "partying" you mean just going out to eat, hanging out with friends, etc., than you probably have time to do that on Friday nights, maybe Saturday nights, and if you have a light workload one week, maybe another night during the week (this happens rarely).
If you mean drinking, however...you won't be doing too much of it. I do plenty of work on Saturdays and Sundays, and I can't afford to get up late/be hungover/etc. from drinking on the previous nights. My friends and I (mostly pre-med) drink perhaps 1-2 times a semester.
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