From an academic perspective there is no bad choice here. Both are very good universities. If I were a hiring manager with a resume from each school, then I would treat both pretty much equally and look for other ways to decide.
How do the finances compare from each school? Would one require larger loans, or would one put more financial stress on your parents? I don't think that either is worth significantly more money compared to the other.
If the cost is the same, then you can start looking at other issues. Do both have good programs in your likely major? Which is closer to home? If you go to university and live on campus and are only located 5 miles from home, it will still feel like an entirely different world compared to living at home.
"help me fall in love with Notre Dame and hate USC."
They are both very good schools. I don't see how any of us can badmouth either of them in general. What is best **for you** is something that we can't say without more information.
This must be terribly stressful. To me it seems horribly unfair that a very high stats student can't have more schools that are "safe". I would hope that university rankings stop using yield and acceptance rate as measures of a school's selectivity. Both can be gamed but are gamed only at the risk of making admissions unpredictable for strong students.
@ClassicRockerDad has some good suggestions. He mentioned a couple of Canadian LACs (although they don't actually use the term "LAC" in Canada). A third one, Acadia, is also still accepting applications. We visited all three a year ago and quite liked all of them. It is too late for financial aid for them, but even without financial aid they only cost about the same as our in-state flagship here in the US -- less than half of the sticker price at New England LACs. If you don't have anything lined up by May 1, then the nacac list of colleges with openings is a good thing to check.
For now I might be tempted to call a couple of safeties where she was waitlisted and see how you can express interest.
I might add (even if this doesn't actually help): Just thinking about your situation I feel like I want to scream. If it were my kid I can't imagine how frustrating this would be.
US Irvine! This is a great school. Many years ago my father wanted me to apply to UC Irvine. There is absolutely no reason to feel bad about going there.
"Important Research Needed before you choose to cut ties completely with family."
Try very hard to never cut ties with family. If ties do get cut then wait a bit then try to retie them. You can disagree very strongly on specific issues, and even find them annoying and insulting and condescending. However, your family is the family that you have, and you can't get another one (other than by getting married and having kids and trying to do better than your parents did).
I might add, for people whose parents don't talk to each other: Try to see if it is possible to stay in communication with both sides, and if you do don't blame either side for not getting along with the other side. Divorce is common and usually too complex for the rest of us (even children) to fully understand.
You have great stats and a good list of reaches. I think that the odds might be better than 50% that you will get in somewhere. I doubt whether Georgetown with an admissions rate under 20% counts as a match, and you certainly don't have a safety. To me your ECs look so so for most of this list of schools.
You need to add two safeties to the list. No school is a safety unless you are willing to go there, and you have run the NPC and can afford to attend.
Note that for a very high stats student reaches are sometimes easier to pick than safeties. This is particularly true when you are going to need substantial financial aid. The top schools claim to meet full need, and are generally very well known. Picking a safety with a good program in your preferred major that meets full need might be easy in some cases but can be hard in other cases.