Chicago's big bet of expanding during the recession (and incurring lots of debt) has clear casualties, as seen in the above.
I will say this, Zimmer et. al. are absolutely tenacious about staying as close to the "first rank" of universities as possible. Other schools have not been nearly as aggressive BUT, notably, have also not seen the same level of upheaval and uncertainty. (I can't remember the last time a top U had a mass round of layoffs - maybe in 2008?)
Interestingly, layoffs are expected to hit about 100 people. Assuming salary/benefits for each person comes to about $100k/person, if President Zimmer and the rest of the senior leadership accepted 50% pay cuts, most of those jobs could be paid.
Either way, if belt-tightening is necessary at Chicago, senior leadership should be tightening their own belts. This is, of course, not happening. Zimmer et al. tend to present as cold when it comes to this.
Here's hoping for a more humane and human next U of C president!