<p>Actually, to qualify this: math is a validation subject, as is Language, so you can skip a sequence if you pass a higher course (or test in to it) and the lower levels are validated. So you could take Calc 2 and not take Calc 1. Just those two subjects.</p>
<p>However, following on @luckie1367’a observation, you still lose credit if you take out of sequence. So, if someone took Calc 2 and then took Calc 1 they would not get credit for Calc 1 because they took it after 2. If they were counting on those units, they lost them and might get under the minimum unit count.</p>
<p>Validation does not apply to sequences outside of math and lang. So if you missed one of a required sequence in, say Physics, it could impact you as the entire sequence may be required.</p>
<p>And I do agree, @bomerr that someone with great ECs may have an edge up, for sure. It depends on the life story and is variable.</p>