23andMe? Ancestry? Has Anyone Tried These DNA Testing Kits?

“you seem to be looking at the “Inherited Conditions” menu item. Under the “Health” menu for 23andMe, I have risk factors listed for”

I don’t have an “Inherited Conditions” menu item. Nor do I have a “Health” menu. My reports are:
Ancestry
Carrier Status (which is what I pulled from)
Wellness (which has things like sleep movement, reaction to caffeine)
Traits (which has things like propensity to have curly hair)

I have searched the entire site and absolutely nowhere can I find the list you are talking about, nor can I find anything dealing with drug reactions. When did you have your 23andme done? Did you have it done a long time ago, when maybe their health battery was deeper than today (before they were banned from providing health info)? I just had mine done in early 2016.

I feel like I’m not explaining myself well. The reports reflect all your genetic history - both maternal and paternal. They reflect YOU.

The ONLY thing you won’t get if you are a woman is the identification of your paternal haplogroup. The haplogroups just tell you where a small portion of your ancestors (your “pure maternal” or “pure paternal” lines) originated thousands of years ago. They are identified by a series of numbers. So my maternal haplogroup is called U5b1b2 and my paternal haplogroup is called G2c.

You can google / wikipedia and find out more about your haplogroups, but it’s at kind of a sweeping 10,000 foot level.

For example, from google / wikipedia, my maternal haplogroup is found mostly in Finland but also in Norway and Ireland. So maybe waaaay back when I have some Finnish ancestry on a pure maternal line, but that doesn’t mean “I’m Finnish” in any meaningful way. My paternal haplogroup is almost always Ashkenazi Jewish – well, I know that already. That’s what I mean. It’s interesting academically, but that’s about it.

Please don’t take the discussion about this to imply that you don’t get anything of value or that you only get your maternal side if you’re a woman and can’t get a male relative to take this test.

@Pizzagirl I just looked at my results and some of them have this notice. “This feature will be retired as customers transition to the new 23andMe.” I had my testing done in 2012.

I can still see my health risks and inherited conditions. It does say the user should update their preferences to be able to access this info.

Pizzagirl is right - it shows everything for a female except the Y chromosome/paternal haplogrouo, which only tells you about one paternal line (e.g. only 1 out of your 4 great-grandfathers; only 1 out of 8 great-great grandfathers…)

I had my 23andMe done a long time ago, perhaps 2009? I also submitted a second sample when they came out with more tests a few years later. I am grandfathered in for the full information. They were asked a couple of years ago by the FDA to limit what they report, and for a while didn’t even give carrier status to new subscribers, but now are adding back slowly as the FDA permits.

I had mine done at 23andme several years ago and I have the Inherited Conditions, Health Risks, Traits and Drug Response sections. 23andme is doing an overhaul of the entire site and is transitioning all accounts to a “new 23andme experience”. My husband’s account has been transitioned but mine hasn’t yet. His account page shows what @pizzagirl is describing and my page is showing like @LBowie is describing. They sent me an email notice to archive all of my health reports so they’ll be available to me after the transition. I had to “unlock” my health reports in order to save them. I don’t think my husband did that, so his health info seems to have disappeared.

I guess this is all a result of the FDA getting after them for offering what appeared to be disease diagnoses.
http://www.newsweek.com/23andme-will-provide-genetic-and-health-information-again-relaunches-expanded-385736

I think I unlocked my info as well, as I can still see it. I decided not to allow them to use the info for research as I don’t want to run the risk, even if it’s supposedly anonymous, that at some point insurers could get access to that info. So didn’t select for them to save the saliva sample or include in research. Was only interested in it for personal info. And the kit was a birthday gift 3 years ago. IT sat here for a year before I opened it :frowning:

Lbowie, maters and patsmom, thank you. That’s very helpful. It sounds like they did really useful stuff prior to the ban, then after the ban was lifted they only rolled out a few things. I am going to call them and find out if they can test my sample for that full battery. Thanks again!!

@Pizzagirl - will you come back let us know what you find out from 23andMe? I was close to clicking the “Buy” button for one of their kits mostly because I want the health information as I already know a lot about my ancestry. If the health information is being limited I don’t know that I want to spend $199…

My parents did the Ancestry DNA test.

A piece of my family history is that my maternal grandmother was an Orphan Train child. There was always some talk that Grandma may have been Jewish. As a proud Catholic she insisted absolutely not. After all she came to the Orphan Train from a Catholic orphanage.

Low and behold my mom’s DNA results shows half Jewish ancestry. Probably a good thing my grandmother was no longer here to learn this. It would have upset her world view.

How timely, I just sent off my kit to Ancestry.com two weeks ago, and I am patiently waiting. I actually grew up with my great grandparents on both sides, with the oldest living until I was in my thirties, my mother grew up with her grandma, so I know of 7 generations that were here in the states. I do however have one paternal great grandfather who was White, and I didnt know, so I am curious if that shows.

Yeah, well, Madeline Albright (born in the today’s Czech Republic) didn’t know she was Jewish either til years later, even though her family hosted / took in a cousin who was sent to live with them while her family perished. So you’re in good company. Welcome to the tribe! (Though I’m only a pseudo-tribe member since it’s not through my mother.)

I am an adoptee and just ordered 23 and Me a few days ago. I’m mainly interested in paternal information since I’ve had some contact with the maternal side. And according to my information, I’m not the only " wrong side of the sheets" child he fathered. I hope to find out more about that.

Even though you can no longer get the detailed health-specific info through 23andme, I believe you can download your genetic info from 23andme (or from the competitor services) and submit it to a third-party service like Promethease to get a detailed health report describing genetic risk factors. The health reports are very inexpensive – like $5 or $10, I believe.

I haven’t done it but I would like to.

I have no idea why 23andme was prohibited from providing the detailed health info but Promethease is able to provide them.

That’s fabulous! I will check out Promethease.

Oi! I just ordered mine last week. I did 23 and me. It seems far more comprehensive than anything Ancestry was offering. And as a person of color, I’m not expecting much physical documentation of where I am from and beyond my great grandparents, it’s all a blur to me. I got the data collection kit maybe 3 days ago. It’s already been shipped out and the 6-8 week waiting game begins!

So my brother did this because SIL is really big with ancestry and included the health information. The only disease he was increased risk for was Alzheimers. It is strong in my family. But, my athletic non-smoking brother died of a heart attack at 56. Take the health stuff with a grain of salt.

23 and me tells you your percent Neanderthal DNA, which is interesting and a bit unnerving if it is higher than average. You also have access to your complete genome ‘raw’ sequence data. With a bit of patience and lots of googling you can search whether you have alleles (gene variants) associated with disease. For example a recent article in the LA Times mentioned a gene variant associated with increased risk of Alzheimer’s. You can search the 23 and me database to find out which gene combinations you have. They aren’t allowed by the FDA to interpret all of the information available but they provide the data you need to do it yourself. I can link more information on how to do it tomorrow when I’m at a computer. There is a site called " How to use 23 and me irresponsibly" that has some tips.

Thanks, momsquad. That’s really good to know. I think I’m going to order the 23andMe tomorrow.

WOW @nottelling! Thanks for the Promethease link! I just ordered it and it took less than 20 minutes to run. The report is thousands of pages long! It’s quite technical, so I need to sit with it and learn a bit more about how interpret, but it does covers lots of diseases - including asthma, arthritis, various cancers, etc.

A few things that stood out for me were:

  • It confirmed that familial dysautonia carrier status that 23andme indicated
  • It indicated I was higher risk for pregnancy-induced hypertension - which I did have
  • It indicated I was higher risk for celiac - which I do not have, but my D does, and it was surprising because no one else in our family appears to have it

Thanks again! Off to learn about it on Reddit …