The guidance counselor at my daughter’s large public high school pointed out last year that a lot of universities do not like DE classes for the purpose of admissions, not even if they are from their own campus. While it sometimes cannot be avoided (e.g. for Foreign Language classes), she pointed out that AP content and test results are nationally more comparable while college course/DE content and grading depends on the instructor and could be everything from extremely excellent to very, very faulty.
I would talk to your guidance counselor. You can probably not go wrong with a good mix between AP and DE.