<p>Nice selective editing–let the folks see the rest</p>
<p>In the middle of dairy country, nestled by four glacial lakes, Madison, Wisconsin is quietly emerging as a biotechnology and life science powerhouse. The state’s capital, Madison is a study in contrasts. Here the Midwest conservative work ethic coexists with the city’s liberal-progressive politics, and scientists at the University of Wisconsin (UW)-Madison enjoy world-class research facilities and an affordable cost of living that colleagues in many other biotech “hotspots” can only dream of.</p>
<p>Indeed, Madison is consistently ranked among the best places to live in the United States by Money magazine and other publications. Last year, Forbes magazine named Madison the number-one city for business and careers based on its strength in education and economy, low rate of unemployment, and affordable living. “It’s a wonderful place to live,” says James Keck, professor of biomolecular chemistry at UW-Madison’s medical school. “It’s a smaller city surrounded by beautiful countryside, yet it has great science and research strengths.”</p>
<p>Wisconsin is home to about 250 biotech and life science companies, employing 20,000 people and posting $5 billion in annual sales. Roughly half the companies are in medical devices and instrumentation, led by GE Healthcare, which has a large medical-imaging manufacturing facility in Waukesha, about an hour’s drive east of Madison. Of the remaining 125 or so biotechs, 80% are located in Dane County, Madison’s major metropolitan area. Fully half of these can trace their roots to discoveries made by researchers at the university.</p>
<p>Return to top </p>
<p>HOOKED ON MADISON
Four years ago, Keck’s postdoc in molecular and cell biology at the University of California-Berkeley was winding down, and he began looking for a faculty position at a major research university. Keck ended up choosing UW-Madison based on the strength of its science and the quality of its community. “We were looking for a nice-sized city where it would be great to raise kids,” Keck says.</p>
<p>Now he’s hooked on Madison. “I’m getting great students, and scientifically I’m not limited by anything but myself,” Keck says. “The public schools are among the best in the country and compared to California, the housing prices are a dream-come-true.” Still, Madison isn’t paradise. “It’s nice having seasons, unlike Berkeley,” Keck says, “but there are times when I wish it were warmer.”</p>
<p>Wisconsin Welcomes New Biotechs</p>
<p>Tom Primiano, president of Clonex Development, a small Chicago-based biotech company that develops therapeutic proteins, knew he wanted to move his lab to Madison. “Our future will be tied to stem cells, and this is the place to be for stem cells,” he says.</p>
<p>Wisconsin was more than happy to help. In February the state gave Primiano $135,000 in venture funds and technology-assistance grants to purchase new equipment and hire technical support staff. Clonex moved into new lab space in Madison’s University Research Park last month.</p>
<p>Wisconsin offers a range of assistance to life science startup companies. Programs include 25% tax credits to angel and venture capital investors who finance qualified new technology companies, especially biotechs. Other assistance includes bridge grants, matching grants, and development loans. The Madison City Council has also passed an ordinance streamlining construction of facilities for biotech research.</p>
<p>“Wisconsin seems to have an interest in fostering biotechs,” Primiano says. “Illinois was behind in helping small companies get what we need.”</p>
<p>In November 2004, Gov. Jim Doyle announced a $750 million, 10-year biotechnology development plan for Wisconsin. Central to this is the Wisconsin Institute for Discovery, a 450,000 sq ft, $375 million interdisciplinary facility that will occupy two full city blocks on the UW campus. The facility will replace older, dilapidated buildings and will have shared research space for biology, bioinformatics, computer science, engineering, nanotechnology, and stem cells. The state legislature is scheduled to vote on Doyle’s budget plan this month.
Okay, so what if the temperature drops to 5</p>