I would use the AP credit for Calculus and try to skip to Calculus 3/Multivariable. Speaking for my son’s current school, he heard some not so pleasant stories about the Calculus 1/2 sequence and how poorly taught it was. The higher level math classes were taught better in his opinion.
His school gave general education credit for a 5 in AP Chemistry only and no course credit, so students couldn’t opt out. I would personally not use AP Chmistry credit to opt out if General Chemistry is taught the same way as his college, where the first semester is an introduction to Physical Chemistry/atomic and orbital structure (aka baby quantum mechanics).