Sure, some. Cornell has an intro Psych class that regularly enrolls 1600, filling the largest auditorium on campus. The tour guides boast about it when you visit. At Harvard, Computer Science 50, Intro to Computer Science I, drew a record-breaking 818 undergrads in the fall of 2014, making it Harvard’s largest class. Second largest was Economics 10a, Principles of Economics, with 711 students. In the spring of 2015, Economics 10b, Principles of Economics, drew 619. Life Sciences 1b, An Integrated Introduction to the Life Sciences, enrolled 464, and Statistics 104, Introduction to Quantitative Methods for Economics, drew 372.
http://www.thecrimson.com/article/2014/9/11/cs50-breaks-enrollment-records/?page=1
http://www.thecrimson.com/article/2015/2/5/study-cards-deadline-enrollment/