I considered U of Rochester / Case and toured Brandeis - I only ended up applying to UR - while I didn’t attend, I still to this day have a very high opinion of the school, and everything you described in what you want fits U of R. I would say its the clear choice. I can’t provide much more information beyond what others have, but I really loved their curriculum designs with the idea of concentrations and a way to allow students to really choose their classes.
For the record, the Brandeis vibe just didn’t fit me at all, and for Case I didn’t like the location enough to apply. Both are good schools and certainly comparable to U of R. I am currently attending Northeastern - U of R was my second or third choice - it was in competition with BU and WPI.