I am U. Chicago and JHU alum. So let me tell you my story about campus safety. UChicago, back when I did my undergrad in the 1980s, was down right dangerous. The campus perimeter was not “marked” but everyone knew, nope, don’t walk alone at night to Cottage Grove station… and never ever walk alone pass south of 60 street… That was in the 1980s. Now, if you ask me, would I be comfortable to send my daughter to UChicago for undergrad. I would have to stop and think hard. Same thing with JHU at Baltimore, when I did my grad there, my goodness, do you even want to get out of the lab 3 am in the morning and walk back to the dorm or the apartment nearby? Again, that was in the late 80s and early 90s, compare to now, those were the better days for those neighborhoods. East Cleveland is definitely not safe to walk alone after dark. Don’t go there. Plan a map to go around that if you want to drive to the campus. I have a friend working at Cleveland Clinic right now and he basically told me the same things as everyone been posted here. The train and the bus can get scary, but as long as you are not alone and late in the evening, then no worry. The campus itself is safe and the University Hospital area is also ok. It is one of those things about an urban school. You just need to be aware of where you are at night, and when travel alone.