You will be compared to your peers. If your peers are taking AP calc and you are not, if your peers are taking AP physics and you are taking honors, that will likely be an issue for the most selective schools on your list.
That being said, I would not take those classes if it will add additional stress that is difficult to manage. Mental health is very important. I would take the classes that you could manage and do well in, and adjust your list accordingly if necessary. I would also speak with your guidance counselor.
Congratulations on your accomplishments!