We did the same. Neither received an application from our son. As you said, both would appeal to the right students, but probably not the same students. The big, multi-major schools are yet another type of experience.
I can see having different sized schools on a list if there are factors that unify them.
Our son’s list looked a little weird with WPI (4000 undergrads) and Utah (30,000) undergrads. Every school on his list was known for going above and beyond to teach practical application of theory, and save one, Cal Poly, the school he actually chose, was near skiing.