Chance me for MIT or Columbia and other colleges (Junior) [3.9 UW, 1540 SAT, Biology/pre-med, TX student]

There might be two questions hiding here. Will this help you for admissions to MIT? That is hard to say one way or another. Will this help you in general to get admitted to a very good university? YES, absolutely for sure.

Also, doing very well on AP chemistry will help you to be ready to do well once you get to university.

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