Is she applying to biomedical engineering or biology? Both will be difficult at her reaches, and both are heavily dominated by females in the applicant pool at most of the schools listed. What subjects were her non-A grades in, and what years of HS did they occur?
CMU is definitely a reach. Purdue and seems like match to me, at best, not a likely. It is highly school dependent: for top20% (but not top 10%), Purdue is a match from the public magnets and the top privates in our area, top 5 or 10% with top rigor would make it a likely.
Georgia Tech in state helps a lot: is it truly a likely though (greater than 75% chance of admission)?
How many students get into ivies/ivy+ from your HS , unhooked(I do not see any hooks unless I missed it)? Is it more or less than 10% of the class? So much of this depends on the high school.
I agree with NUPM that finding schools that are similar in vibe to the reaches may make more sense, especially if flexible for Bio vs BME. For example, William&Mary could be a match (greater than 25% chance, less than 75%) , same with Wake Forest, Emory, Boston College.