<p>@Trannay - You can check this out, but it is my understanding that the vast majority of med schools in the US WILL NOT allow you to substitute an AP score of 4 or 5 for general chem, but REQUIRE that you take it in college. So much of this other discussion could be partly moot if I am correct. Check the web sites of the top 30 or so med schools, and ask the pre-med advisors at a 4 year university that has a lot of pre-med students.</p>