In general, the lower the acceptance rates the more difficult it is to be accepted. You need to review the colleges common data sets to see what the average GPA and test scores are for each college and if your score are within the range of accepted students.
Lastly, if your are asking if the college has “higher difficulty” once accepted, the answer is probably yes. The expectations are high and the student body will be stronger. It also depends on major and college within the university.