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<p>You have a lot of options if you use a plane. </p>
<p>Macalester is within that time frame. You have to fly to Minneapolis St-Paul, but it’s only a 90 minutes flight and the college is not far from the airport. </p>
<p>UChicago is even easier with Southwest to Midway Airport. </p>
<p>Tulane, Rice, UPenn, Swarthmore, and Johns Hopkins, and Duke all may be within 3-3.5 hours door to door depending on how close you live to the airport. </p>
<p>Not sure why you’ve ruled out Truman State which is in Kirksville, MO and is 3.5 hours from St Louis.</p>