I think there are a couple of things to address here:
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First of all you made it to Berkeley, that’s amazing congratulations! You mentioned you weren’t really enjoying yourself,but that is something that you can definitely remedy. The first thing to recognize is that college is definitely harder than high school, but honestly you are doing great. You should be proud of that 3.77 GPA. It is practically an A at one of the most rigorous schools in the country. Trust me, I have plenty of friends applying to med school and that is a fantastic place to be at, especially for a really rigorous school like Berkeley.
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You can make a change. You are not in this alone. You can study with other people, seek out professors in their office hours, or seek other academic resources. Also with the extra time you save from collaboration, you can explore and find new things that you enjoy at your college. There is plenty to look out for and try.
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The other things are just things that you will have to learn about yourself and the world around you. Coming to college, you probably won’t be the smartest person in the room anymore. And that is okay! And perfectly healthy. You don’t need to be in order to get where you want to go. Many, many students feel this once they have entered a top college because there are a lot of smart people in the world. It’s not always a competition.
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I think that you should communicate to your roommate that you would prefer her not to ask all about grades all the time. Perhaps share that it gives you anxiety and that you would rather not add to it. Or better yet if you are in the same classes all the time, suggest that you study together. Otherwise asking for a new roommate or transferring rooms is always an option.
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It sounds like you are going through some other issues that it would be helpful to talk to someone about. Have you considered going to your school’s counseling center? They can be immensely helpful. From experience, they can help address many of the things you are talking about or find healthy ways to cope. Please at least consider it if you haven’t already.
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I think one thing that may help with your feelings of not necessarily being close to anyone is joining clubs or organizations, or taking time to get to know some new people if you haven’t already. Romance is honestly overrated and having strong relationships, whether it be with friends or other loved ones is important. But that requires you to go out there and find some of those people. This is coming from a person that didn’t really date anyone at all until senior year of college. Once you do, you realize that the relationships that you have before are super important and those feelings of insecurity is all in your head, although I understand how powerful they can be.
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In your next semester find just one or two professors that seem like they care and that you click with. Seek them out, come talk to them, about your interests and that will happen naturally. Finding a mentor in college, maybe it is your college advisory or someone else that can advocate for you, is a helpful part of the process.
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You’re not alone, there’s people that can help. Many of the concerns are currently ones that are bubbling up inside your head and I think talking about it, whether it be with a counselor or with someone else you trust, would help a lot. Once you do, you may figure out ways to address them or at least find that person you are close to. Many of those things you have mentioned whether it be insecurity or questioning relationships are things that many other people have gone through before, myself included, but you gotta be brave and reach out.
It sounds like many of the things you are mentioning are not necessarily Berkeley specific, but ones that you would have to deal with regardless of the institution, so that’s why looking at those first would be helpful