<p>It depends in large part on how good you are at scheduling and whether you mind working up until your flight. I tend to procrastinate a lot on writing papers, and I always used to schedule my flights for Friday afternoon. The result was that I always would have to pull an all-nighter Thursday night. When I started flying home on Saturday, it was much nicer because I had time to relax and pack after finals were due, plus people often like to go out and celebrate on that Friday night.</p>