I work in IT. Anyone we hire new out of college will have to have a computing major. We do hire people with experience in lieu of education + a degree in some other discipline (like me, my major was medieval history long enough ago that I joke it was current events). But by and large, we don’t hire kids who are self-taught.
Self-taught programmers have an extra hurdle to jump getting into the business. Many jobs are gotten through nepotism, of course, so if you’re self-taught and you have friends in the business maybe you can still make it as a programmer.
Also in my experience self-taught programmers often have terrible habits when it comes to collaboration, documentation, and code review.