How Does the University of California Major and Alternative Major Preference Work In Practice? Strategies?

Colleges & Universities University of California - GENERAL
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If there are multiple majors offered by the same department (like CS/CS+Business/DS) then you can apply to the major that is easier to get in. Usually changing the major within in the same department is easy.

Edit: In these cases the core curriculum is the same and you do not necessarily have to change the major.