Many states have a single math and a single ELA exam, some use the SAT. Many of these do not indicate a grade for their state assessments on the transcript.
If your other grades and scores are high, for example ACT, SAT, AP, etc., they aren’t thinking, “But where is the missing Algebra II Regents score?”
The biggest issue is the hit to the final class grade and how they note the absence. OP will have to talk to her district to see how they handle it, which will likely depend on the reason she missed and the district’s policies.