<p>What do you mean by him switching majors? He doesn’t have to major in bio…he can major in anything he likes and fulfill his premed courses. As far as getting less than a B in college…there have been several successful med students here on CC (Bluedevilmike for one) that got less than that and still got into medschool. My daughter got a C+ in an UG class (gasp, jk) and still got into medschool. I also wouldn’t advise him to skip gen chem 1.</p>