If you want to major in science, then you can try to replace AP econ with APBio, but it’ll be significantly more work, perhaps too much.
Senior year you could take honors English and social science (not AP) to take AP bio and AP chem, then Calc Ab and Ap French, and your schedule would be full. AP chem is one of the hardest APs there is. If you were to move toward business or econ or other social sciences as a major, then your senior schedule would be good with just AP bio but + AP econ and AP Gov.