Bio has a dreadful combination of high selectivity for a college major (like CS) and low employability/professional outcomes (too many failed premeds, not enough jobs for a Bio BS.)
In terms of selection, with a 4.0 and good rigor, even for bio sciences and their high competition, he’s likely to end up at a UC, even if UCR.
However the lack of AP Bio and AP do not concern me for admission but rather for adequation between what he thinks he wants to study and what he knows about the subject. Choosing a major solely based on a freshman year experience with the subject is akin to choosing a math major because you liked Algebra1 and geometry, without any idea whether you’d like precalculus or calculus. Students do it all the time, of course, but studying something that’s not what you thought it’d be is a big reason for so many stem students switching, who fortunately can often try something else, but looking at ease of switching should them be a big concern.
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