Depression get even worse during residency.
From my earlier thread, posted in December–
Medical students, residents and physicians all have a much higher rate of suicide than their age-peers, in part because they tend to choose more successful methods to kill themselves and have better access to potentially lethal drugs.
http://emedicine.medscape.com/article/806779-overview
Overall female physicians/residents/med students have a higher suicide rate than their male colleagues, not because they attempt suicide more often than their male counterparts (suicide attempts are more or less even distributed between male and female) , but because they choose more lethal methods for their attempts.
When I am asked by mothers of pre-meds if I am thrilled and excited to have 2 daughters who are physicians, I always say "no"-- which earns me some very strange looks. While I am extremely proud of my daughters' success and all the sacrifices each made for their careers, I know that their risk for depression, suicide, and divorce are significantly higher than their equally educated professional peers. I view their careers with very mixed feelings-- and sometimes wonder if they would have better off as engineers or research scientists.