Senior year my daughter had signed up for Spanish 4…but when doing a summer AP Bio prep program her teacher was telling her how great Anatomy and Physiology would be (which that teacher also teaches) …As my daughter wants to be a doctor, she chose to take A&P. I personally think HS should be about exploring options as well as taking advanced classes.
But like others say, you have to take into account what possible (realistic) colleges you are interested might require.