<p>The adcoms may not notice that you didn’t take any AP science classes, and not doing so wouldn’t work against you. HOWEVER, just by looking at your schedule, anyone can see that not only are you not taking any AP science classes, but no AP math classes either. Thus, you should definitely take at least one, probably two, of either math or science AP classes. There could be dozens of reasons that you didn’t take any AP science classes, but not taking AP math OR science is no coincidence; it is quite obvious that those are your weaknesses, and you failed to challenge yourself in your weak subjects, which may be looked down upon.</p>