This is late haha but I would definitely recommend going the LSM route. I was accepted to LSM last year even though I did not choose to attend, it is an absolutely exceptional program with great mentors/connections to big pharma/biotech and the unique capstone course at the end. FYI a LARGE amount of LSM are actually premed/MD PHD and there are a lot of resources to help you go that path (one of the upperclassman was one of the few people in the US that got a perfect score on his MCAT). I have a couple friends doing M&T and I can’t say the same for that dual program. I feel like LSM provides the perfect balance of courseload (it isn’t much harder than the normal Penn student) while leaving lots of room for extracirriculars and internships (which they HOOK you up with) and providing a close-knit group/community and lots of good connections for the future.