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<p>Yes, I see what you mean. (I wasn’t sure if you thought even a glass of wine once a week would have been inappropriate.) I know somebody rather like that. She’s on significant doses of seroquel, lithium, lamictal, adderall (because she also apparently has chronic fatigue syndrome - ha - she parties until 3AM pretty much every third night), and always takes ambien to fall asleep. Anyway, whenever she goes out she gulps down shots like a huge man who’s been building up his tolerance for years. So, it’s possible, but I know it must absolutely destroy any good her meds would do, and even if she weren’t on those meds it would mess her up and slowly kill her anyway.</p>