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<p>My wife got psoriatic arthritis as a relatively young woman (afaik, well before the biologicals of today were available). It was kept under good control with relatively benign medication (interestingly enough, gold capsules worked well). As you probably know, many autoimmune diseases go into remission during pregnancy (but you must stop taking many of the meds 6 months before you try to become pregnant). After our first child, the meds again worked well. After our second child, none of the old meds worked at all. </p>
<p>After a brief try with Humira, which was not well tolerated, my wife has been taking Enbrel at a slightly higher dosage (once every 5 days rather than 7). Her rheumatologist says that it’s the reason my wife still runs marathons (albeit pretty slowly) rather than being confined to a wheelchair. </p>
<p>We have a high deductible health plan, which works well for us. The good news and the bad news is that we are finished with our out-of-pocket spending before March is over. It is a sufficiently life changing medication that we would (since we’re able to) pay for it all year if we had to. </p>