I wouldn’t worry too much about it. As with any city you learn where and where not to go, how to best stay safe, etc. My D and I toured there a couple years ago. The campus was one of the most bustling, busy campuses we saw during that time. My D grew up in Oakland and now attends college in Chicago, so she is familiar with high-crime cities, but she knows which areas to avoid in both cities, how to be safe, carries a birdie, etc. I wouldn’t have worried too much about her if she had chosen SLU.
@Malsandhuskies D is at SLU, very happy there. Maybe she’ll chime in.