Perhaps not, but it is a negative not to read the website and follow directions.
The Harvard admissions website states (for domestic applicants): “Please note that we will reach out to you if we would like to schedule an interview. You do not need to take any additional actions to set up an admissions interview. If an interview cannot be arranged, you will not be at a disadvantage during the application process.”
If you ask a general question, they won’t know your name and won’t have to spend a lot of time. If you ask for an interview, they will need to take down your name and spend time.