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<p>This is stated in the FAQ page. For sure they deduct 1/4 point for every wrong answer. ISEE questions have four choices and don’t penalize for wrong answers.</p>
<p>Statistically speaking, if a student has no clue about a question, it’s best to leave it unanswered. If he can eliminate one false choice, he evens out over many questions, so there’s no harm for guessing. If he can eliminate two or more, he should definitely guess!</p>