OP here. So many great suggestions! Ones that we’ve visited with his siblings that were already on our radar but you’ve all just reaffirmed as to my initial thoughts when we visited:
U of Dayton
Susquehanna
Butler
Miami Ohio (brother almost attended)
Xavier
U of Scranton
Gettysburg
Loyola Maryland
Hobart
Marist
When he was 12 we did a PA road trip with his sister. Susquehanna was the first school we visited. I do remember him announcing after 5 minutes “this place is beautiful, this is where I’m going to college!” Maybe it was fate! 
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Lots of other great suggestions to check out!
Anyone have firsthand knowledge about the friendliness levels at Catholic University? My D and I D really liked it. Not sure if the kids at Catholic all kind of scatter into the city on weekends.
I don’t think S is opposed to greek life, his brother is in a frat and I think it could be a good way for him to make connections but it’s not a requirement either.