Already been covered, but I was just going to note that Rochester has a “normal” Department of Music in addition to Eastman, and one of the cool things about the Rochester curriculum structure is you can do what they call a cluster in Music, or upgrade it to a Minor or second Major depending on how far you end up wanting to go with it:
Case Western also offers majors (some explicitly designed to be combinable) and a minor in Music, and I believe the Music minor is non-auditioning. But they do not have the same cluster program, and they generally have a more standard distributional-type gen ed requirement:
I would also echo that I think of the City of Rochester as being a real city, and the River (Main) Campus is quite close to the city center, but also sort of enclosed–it is in a bend in the river and then the land side is mostly across from a large cemetery. Case Western is actually farther from the center of Cleveland, but it is obviously a bigger city overall, and their campus definitely feels more integrated into the urban landscape.
Otherwise, these are both popular options from our HS, and the reputation is Rochester is a nicer/more academicky college, and Case Western a little more individualistic/pre-professional. Obviously not a lot of people have a true basis for comparison, but I think that tracks enough commentary I have seen that it might have something to it.
In the end I think academically these are more similar than different, and visiting both seems like a very good idea. But I kinda think your kid does sound more like what we would think was a Rochester kid (mine too, by the way–he ultimately applied to Rochester but not Case Western, with an interest in Bio but also possibly Classics and a general desire to explore).