First, hugs go out to you. It’s tough. I know lots of Ds who have had bumpy freshman years with loneliness, friend drama, grade stress, etc. I’d wager that YOU get the brunt of her angst and it might not be quite as bad as she paints it. She needs SOMEONE she can vent to, share her fears with, etc. and you should be glad it’s you–hard as it is.
Suggestions, most already made: 1) go to counseling center 2) join a new club that gets out and actually does stuff 3) get transfer applications out so she’ll have options should she still be unhappy this spring. Suggest she randomly introduce herself to one new person a week and ask if she can sit with him/her at a meal, study together, etc. Suggest she go one new place a week she hasn’t been before. In other words, she needs to risk putting herself out there a bit more.
If at all possible, I do think she should try to finish the year. Continue to listen. You know your D and will know if/when you need to get more involved. I’d also make sure I had the contact number for her RA in case you were ever concerned and needed to be in touch.
Both of ours had bumpy, parental stress-inducing first years for different reasons. Sophomore year is better and they seem better able to cope with the ebb and flow of things.
Keep us posted and good luck.