You should expect that practically all East Coast schools will draw a majority of their students from the East Coast. You can see a geographic profile of Villanova students at the following link, although I don’t know how current it is:
According to that source, most Villanova undergrads (58.8%) are from PA/NJ/NY. If you add in MA/CT/MD, the total rises further (to 78.1%). It’s probably over 80% if you throw in little northeastern states like ME/NH/VT/RI/DE.
There will be some Midwesterners at a school like Villanova, but not a lot. If you go to any East Coast school, you should be prepared to adapt.