<p>If BME is really your thing, you definitely can get through okay. Most classes do curve grades according to how the class does. While the grades will rarely be inflated, they will generally be curved to above a C anyways, usually to a B-. So, even if you get lower number grades because of the course difficulty, your actual grades won’t necessarily be worse. There definitely is some grade deflation, but nothing that some extra studying cannot overcome either. I have a friend who is premed and has over a 3.8 going into Junior Year. It is possible. It just takes work.</p>