My daughter is a freshman majoring in neuroscience with thoughts of some kind of healthcare career (doc, PA, research - not sure). She took regular chem in high school, did AP bio, but not AP chem. She was thrilled that on the first exam in chem at BU (CH 101), she received a 64 when the average was in the low 30s. She ended up with a B for her first semester. That said, she came from a high school with very high demands and an extremely heavy work load with lots of homework (and she danced tons of hours each week outside of school). She said that lots of kids in chem 101 at BU complained about how much work it was. She felt very prepared thanks to her unforgiving high school teachers - ha - and thought it was pretty much like her classes in high school. That said, your child needs to be ready to put in lots of hours. They will watch their friends with much lighter schedules (but the same number of credits) have much more free time. This semester she has two classes with labs (so even more time in the classroom), yet she is participating in dance performances (with some rehearsals that are 9-11 p.m. during the week and one that rehearses every weekend), and she loves to go to hockey games. Keep in mind that she is a smart girl, but someone who has to work for her grades.