::sigh::
This is why we can’t have nice things.
Clemson is a major flagship university in a smallish upstate town in the South. As such, you’ll run into a lot of things: temperate winters, curvy roads, a darn fine football team, amazing architecture and enhineering programs, and a lot of fraternities and sororities, but also a lot of kids who belong to neither. (Also big orange tiger paws on the roads. My kids loved them when we’d take them to Homecoming.)
If you’re from Boston or Brooklyn, chances are Clemson will be less diverse than home. (If you’re from Corning or Naugatuck, not so much.) You will probably have a hard time finding really good felafel, but a much easier time finding good barbecue, though it won’t look much like that stuff they serve at Chili’s.
People read books, travel (even out of the country!), worship the deity of their choice or none at all (though it will usually be the Christian God, just like most of the US), speak a second language (and English fluently, though yeah, your child may pick up “y’all” as a form of address, it’s hard not to, even for Northeasterners), listen to a wide variety of music, and even wear shoes when appropriate.
People in the theatre department may or may not want to work for mega-churches. I’ve no idea. There’s big money and actual employment in that arena, so it’s possible, job prospects being what they are for theatre majors. And honestly, if you want to break into Broadway, Oklahoma City U or FSU or Steinhardt are better choices.
Arts are somewhat less funded at Clemson because-- like most states with binary flagships-- one school (Clemson) was the men’s uni originally and the other (USC) the women’s uni, and consequently strengths follow what one would expect from early 20th century sexist focus. However, if she’s into sciences, engineering, or architecture, she’s in good shape. However, if she’s an engineering major who just likes live music, it’s not hard to find.
You may, at some point, run into a stereotype of the sort Dusty describes. (They may even be from SC, but not necessarily.) Now, I’m going to assume Dusty isn’t the actual source of those stereotypes as s/he says “described to me…by Northerners”. All I really have to say about those kind of folks is that they’re probably about as representative of Clemson as Snooki from Jersey Shore is of the Northeast. She exists, but she’s not Everyyankee-- nor should anyone expect her to be.
Honestly, my experience is you get what you put out there. People won’t make a big deal about your child being “from off” unless your child makes a thing about it. The biggest thing she may run into is people commenting on her accent or finding out the hard way that all tea is sweet tea unless otherwise specified.